Our new Clear+ tissue clearing technique is the only real system that delipidates samples without any alter in morphology and with minimal influence on structural integrity.
Our convert-key SmartBatch+ procedure brings together electrophoretic tissue clearing and immunolabeling into 1 superior-throughput system.
Antibodies may perhaps just take months to diffuse by way of only some millimeters of tissue, by using a steep labeling gradient from surface to core.
Megatome is suitable for accuracy: the blade vibrates at an increased frequency and larger amplitude array than other microtomes, and includes a exceptional deflection Manage system.
SE utilizes a rotational electrical industry to disperse highly electromobile molecules (including antibodies or surfactant micelles) in the course of a porous sample without harmful electrically billed buildings within the tissue. This enables 2-four working day clearing of intact organs,
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Megatome is actually a novel microtome that permits for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with small tissue injury and information loss.
It’s time and energy to improve your microtome to Megatome. With accurate significant-frequency slicing for an unmatched array of sample sizes and kinds – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various applications.
Totally delipidate full mouse brains or comparably sized samples in just one working day with SmartBatch+, or in a single week with our passive clearing package.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, protecting specimens for several rounds of processing.
Leverage the Very clear+ tissue clearing strategy, coupled with eFLASH and patented stochastic electrotransport systems, to promptly very clear and label complete organs. Essential highlights and capabilities involve:
Our novel Protect tissue preservation system sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.